Preclinical Evaluation of an 131I-Labeled Benzamide for Targeted Radiotherapy of Metastatic Melanoma
نویسندگان
چکیده
منابع مشابه
Preclinical evaluation of an 131I-labeled benzamide for targeted radiotherapy of metastatic melanoma.
Radiolabeled benzamides are attractive candidates for targeted radiotherapy of metastatic melanoma as they bind melanin and exhibit high tumor uptake and retention. One such benzamide, N-(2-diethylamino-ethyl)-4-(4-fluoro-benzamido)-5-iodo-2-methoxy-benzamide (MIP-1145), was evaluated for its ability to distinguish melanin-expressing from amelanotic human melanoma cells, and to specifically loc...
متن کاملPreclinical Evaluation of an I-Labeled Benzamide for Targeted Radiotherapy of Metastatic Melanoma
Authors' A Massachu 3Johns Ho Schering 5Radiation University, Correspon ticals, 160 Fax: 617-8
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2010
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-09-4414